Amphetamine can be habit-forming. Do not take a larger dose, take it more often, or take it for a longer time than prescribed by your doctor. If you take too much amphetamine, you may continue to feel a need to take large amounts of the medication, and you may experience unusual changes in your behavior. You or your caregiver should tell your doctor immediately, if you experience any of the following symptoms: fast, pounding, or irregular heartbeat; sweating; dilated pupils; abnormally excited mood; restlessness; irratibility; difficulty falling sleeping or staying asleep; hostility; aggression; anxiety; loss of appetite; loss of coordination; uncontrollable movement of a part of the body; flushed skin; vomiting; stomach pain; or thinking about harming or killing oneself or others or planning or trying to do so. Overusing amphetamine may also cause serious heart problems or sudden death.

Tell your doctor if you or anyone in your family drinks or has ever drunk large amounts of alcohol, uses or has ever used street drugs, or has overused prescription medications. Your doctor will probably not prescribe amphetamine for you.

Do not stop taking amphetamine without talking to your doctor, especially if you have overused the medication. Your doctor will probably decrease your dose gradually and monitor you carefully during this time. You may develop depression and extreme tiredness. if you suddenly stop taking amphetamine after overusing it.

Do not sell, give away, or let anyone else take your medication. Selling or giving away amphetamine may harm others and is against the law. Store amphetamine in a safe, preferably locked, place so that no one else can take it accidentally or on purpose. Keep track of how many tablets or how much suspension (liquid) are left so you will know if any are missing.

Your doctor or pharmacist will give you the manufacturer’s patient information sheet (Medication Guide) when you begin treatment with amphetamine and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website ( to obtain the Medication Guide.

🔔 Why is this medication prescribed?

Amphetamine (Adzenys ER, Adzenys XR, Dyanavel XR, Evekeo, Evekeo ODT, others) is used as part of a treatment program to control symptoms of attention deficit hyperactivity disorder (ADHD; more difficulty focusing, controlling actions, and remaining still or quiet than other people who are the same age) in adults and children. Amphetamine (Evekeo, others) is also used to treat narcolepsy (a sleep disorder that causes excessive daytime sleepiness and sudden attacks of sleep). Amphetamine (Evekeo, others) is also used for a limited period of time (a few weeks) along with a reduced calorie diet and an exercise plan for weight loss in obese people unable to lose weight. Amphetamine is in a class of medications called central nervous system stimulants. It works by changing the amounts of certain natural substances in the brain.

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🔔 How should this medicine be used?

Amphetamine comes as an immediate-release tablet (Evekeo), an orally disintegrating tablet (tablet that dissolves quickly in the mouth; Evekeo ODT), an extended-release (long-acting) orally disintegrating tablet (Adzenys XR), and as an extended-release (long-acting) suspension (Adzenys ER, Dyanavel XR) to take by mouth. The extended-release suspension is usually taken once daily in the morning with or without food. The orally disintegrating tablet is usually taken once daily in the morning with or without food or liquid. The extended-release orally disintegrating tablet is usually taken once daily in the morning with or without food. For treatment of ADHD or narcolepsy, the immediate-release tablet is usually taken with or without food one to three times daily, 4 to 6 hours apart, with the first dose in the morning. For weight loss, the immediate-release tablet is usually taken 30 to 60 minutes before meals. Amphetamine should not be taken in the late afternoon or evening because it may cause difficulty falling asleep or staying asleep. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take amphetamine exactly as directed.

Swallow the extended-release tablets whole, do not chew or crush them.

Do not try to push the orally disintegrating tablet (Evekeo ODT) or the extended-release orally disintegrating tablet (Adzenys XR) through the blister pack foil. Instead, use dry hands to peel back the foil packaging. Immediately take out the tablet and place it in your mouth. The tablet will quickly dissolve and can be swallowed with saliva. No water is needed to swallow the tablet.

Shake the extended-release suspension (Adzenys ER, Dyanavel XR) well before each use to mix the medication evenly.

Do not add the extended-release suspension (Adzenys ER) to food or mix it with other liquids.

It is important to use an oral syringe (measuring device) to accurately measure and take your dose of the extended-release suspension. Ask your pharmacist for a device if it was not provided. Wash the oral syringe thoroughly after each use.

If you or your child are taking amphetamine for ADHD, your doctor will probably start you on a low dose of amphetamine and increase your dose gradually, every 4 to 7 days, depending on the medication. Your doctor may tell you to stop taking amphetamine from time to time to see if the medication is still needed. Follow these directions carefully.

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If you are taking amphetamine for narcolepsy, your doctor will probably start you on a low dose of amphetamine and increase your dose gradually, not more often than once every week. Follow these directions carefully.

The medication in each product is absorbed differently by the body, so one amphetamine product cannot be substituted for another product. If you are switching from one product to another, your doctor will prescribe a dose that is best for you.