Ceftriaxone Injection

Ceftriaxone injection is used to treat certain infections caused by bacteria such as gonorrhea (a sexually transmitted disease), pelvic inflammatory disease (infection of the female reproductive organs that may cause infertility), meningitis (infection of the membranes that surround the brain and spinal cord), and infections of the lungs, ears, skin, urinary tract, blood, bones, joints, and abdomen. Ceftriaxone injection is also sometimes given before certain types of surgery to prevent infections that may develop after the operation. Ceftriaxone injection is in a class of medications called cephalosporin antibiotics. It works by killing bacteria.

Antibiotics such as ceftriaxone injection will not work for colds, flu, or other viral infections.Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

🔔 How should this medicine be used?

Ceftriaxone injection comes as a powder to be mixed with liquid, or as a premixed product, to be injected intravenously (into a vein) over a period of 30 or 60 minutes.Ceftriaxone injection can also be given intramuscularly (into a muscle). It is sometimes given as a single dose and sometimes given once or twice a day for 4-14 days, depending on the type of infection being treated.

You may receive ceftriaxone injection in a hospital or doctor’s office, or you may administer the medication at home. If you will be receiving ceftriaxone injection at home, your healthcare provider will show you how to use the medication. Be sure that you understand these directions, and ask your healthcare provider if you have any questions.

You should begin to feel better during the first few days of your treatment with ceftriaxone injection. If your symptoms do not improve or get worse, call your doctor.

If you will be using more than one dose of ceftriaxone injection, use the medication until you finish the prescription, even if you feel better. If you stop using ceftriaxone injection too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

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🔔 Other uses for this medicine

Ceftriaxone injection is also sometimes used to treat sinus infections, endocarditis (infection of the heart lining and valves), chancroid (genital sores caused by bacteria), Lyme disease (an infection that is transmitted by tick bites that may cause problems with the heart, joints, and nervous system), relapsing fever (an infection that is transmitted by tick bites that causes repeated episodes of fever), shigella (an infection that causes severe diarrhea), typhoid fever (a serious infection that is common in developing countries), salmonella (an infection that causes severe diarrhea), and Whipple’s disease (a rare infection that causes serious problems with digestion). Ceftriaxone injection is also sometimes used to prevent infection in certain penicillin-allergic patients who have a heart condition and are having a dental or upper respiratory tract (nose, mouth, throat, voice box) procedure, patients who have fever and are at high risk for infection because they have very few white blood cells, close contacts of someone who is sick with meningitis, and in people who have been sexually assaulted or who have been bitten by humans or animals. Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

🔔 What special precautions should I follow?

Before using ceftriaxone injection,

• tell your doctor and pharmacist if you are allergic to ceftriaxone; carbapenem antibiotics; other cephalosporin antibiotics such as cefaclor, cefadroxil,cefazolin (Ancef, Kefzol), cefdinir, cefditoren (Spectracef), cefepime (Maxipime), cefixime (Suprax), cefotaxime (Claforan), cefotetan, cefoxitin (Mefoxin), cefpodoxime, cefprozil, ceftaroline (Teflaro), ceftazidime (Fortaz, Tazicef, in Avycaz), ceftibuten (Cedax),cefuroxime (Zinacef), and cephalexin (Keflex); penicillin antibiotics, or any other medications.Also tell your doctor if you are allergic to any of the ingredients in ceftriaxone injection. Ask your pharmacist for a list of the ingredients.
• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: chloramphenicol, and warfarin (Coumadin, Jantoven).
• tell your doctor if your child was born prematurely or is younger than 4 weeks of age. Your doctor may not want your baby to receive ceftriaxone injection.
• tell your doctor if you or if you have or have ever had any kind of allergies, problems with your digestive system especially colitis (inflammation of the large intestine), malnutrition (you do not eat or cannot digest the nutrients needed for good health), problems with your vitamin K levels, or kidney or liver disease.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using ceftriaxone injection, call your doctor.

🔔 What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.