Cidofovir Injection

Cidofovir injection can cause kidney damage. Tell your doctor if you have or have ever had kidney disease. Tell your doctor if you are taking or have recently taken any other medications that may cause kidney damage, some of which include amikacin, amphotericin B (Abelcet, Ambisome), foscarnet (Foscavir), gentamicin, pentamidine (Pentam 300), tobramycin, vancomycin (Vancocin), and nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Naprosyn, Aleve). Your doctor will probably tell you not to use cidofovir injection if you are taking or using one or more of these medications.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests before, during, after your treatment to check your response to cidofovir injection.

Cidofovir injection has caused birth defects and problems with sperm production in animals. This medication has not been studied in humans, but it is possible that it may also cause birth defects in babies whose mothers received cidofovir injection during pregnancy. You should not use cidofovir injection while you are pregnant or plan to become pregnant unless your doctor decides that this is the best treatment for your condition.

Cidofovir injection has caused tumors in laboratory animals.

Talk to your doctor about the possible risks of using cidofovir injection.

🔔 Why is this medication prescribed?

Cidofovir injection is used along with another medication (probenecid) to treat cytomegaloviral retinitis (CMV retinitis) in people with acquired immunodeficiency syndrome (AIDS). Cidofovir is in a class of medications called antivirals. It works by slowing the growth of CMV.

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🔔 How should this medicine be used?

Cidofovir injection comes as a solution (liquid) to be injected intravenously (into a vein) by a doctor or nurse in a medical facility. It is usually given once every 2 weeks. The length of treatment depends on your body’s response to the medication.

You must take probenecid tablets by mouth with each dose of cidofovir. Take a dose of probenecid 3 hours before receiving cidofovir injection and again 2 and 8 hours after your infusion is completed. Take probenecid with food to reduce nausea and stomach upset. Ask your doctor or pharmacist if you have any questions about how these medications should be taken together.

🔔 Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

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