Granisetron Transdermal Patch

Granisetron transdermal patches are used to prevent nausea and vomiting caused by chemotherapy. Granisetron is in a class of medications called 5HT₃ inhibitors. It works by blocking serotonin, a natural substance in the body that causes nausea and vomiting.

🔔 How should this medicine be used?

Granisetron transdermal comes as a patch to apply to the skin. It is usually applied 24 to 48 hours before chemotherapy begins. The patch should be left in place for at least 24 hours after chemotherapy is finished, but should not be worn continuously for longer than a total of 7 days. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Apply transdermal granisetron exactly as directed. Do not apply more patches or apply the patches more often than prescribed by your doctor.

You should apply the granisetron patch to the outer area of your upper arm. Be sure that the skin in the area where you plan to apply the patch is clean, dry, and healthy. Do not apply the patch to skin that is red, dry or peeling, irritated, or oily. Also do not apply the patch to skin that you have recently shaved or treated with creams, powders, lotions, oils, or other skin products.

After you apply your granisetron patch, you should wear it all the time until you are scheduled to remove it. You may bathe or shower normally while you are wearing the patch, but you should not soak the patch in water for long periods of time. Avoid swimming, strenuous exercise, and using saunas or whirlpools while you are wearing the patch.

If your patch loosens before it is time to remove it, you may apply medical adhesive tape or surgical bandages around the edges of the patch to keep it in place. Do not cover the entire patch with bandages or tape, and do not wrap bandages or tape all the way around your arm. Call your doctor if your patch comes more than half-way off or if it becomes damaged.

To apply the patch, follow these steps:

1. Take the foil pouch out of the carton. Tear open the foil pouch at the slit and remove the patch. Each patch is stuck onto a thin plastic liner and a separate rigid plastic film. Do not open the pouch in advance, because you must apply the patch as soon as you remove it from the pouch. Do not try to cut the patch into pieces.
2. Peel the thin plastic liner off of the printed side of the patch. Throw the liner away.
3. Bend the patch in the middle so that you can remove one piece of the plastic film from the sticky side of the patch. Be careful not to stick the patch to itself or to touch the sticky part of the patch with your fingers.
4. Hold the part of the patch that is still covered with the plastic film, and apply the sticky side to your skin.
5. Bend the patch back and remove the second piece of plastic film. Press the entire patch firmly in place and smooth it down with your fingers. Be sure to press firmly, especially around the edges.
6. Wash your hands right away.
7. When it is time to remove the patch, peel it off gently. Fold it in half so that it sticks to itself and dispose of it safely, so that it is out of the reach of children and pets. The patch cannot be reused.
8. If there is any sticky residue on your skin, wash it away gently with soap and water. Do not use alcohol or dissolving liquids such as nail polish remover.
9. Wash your hands after you handle the patch.

Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.

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