Omalizumab Injection
Omalizumab injection may cause serious or life-threatening allergic reactions. You may experience an allergic reaction immediately after receiving a dose of omalizumab injection or up to 4 days later. Also, an allergic reaction can occur after you receive the first dose of medication or at any time during your treatment with omalizumab. Tell your doctor if you are allergic to omalizumab injection, and if you have or have ever had food or seasonal allergies, a serious or life-threatening allergic reaction to any medication, or sudden breathing problems.
You will receive your first dose of omalizumab in a doctor’s office or medical facility and additional doses until your doctor feels that you are safe to receive omalizumab at home. You will stay in the office for some time after you receive the medication so your doctor can watch you closely for any signs of an allergic reaction. Tell your doctor if you experience any of the following symptoms: wheezing or difficulty breathing, shortness of breath, cough, chest tightness, dizziness, fainting, fast or weak heartbeat, anxiety, feeling that something bad is about to happen, flushing, itching, hives, feeling warm, swelling of the throat or tongue,throat tightness, hoarse voice, or difficulty swallowing. Call your doctor immediately or get immediate emergency medical attention if you experience any of these symptoms after you leave your doctor’s office or medical facility.
Your doctor will give you the manufacturer’s patient information sheet (Medication Guide) each time you receive an injection of omalizumab. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer’s website to obtain the Medication Guide.
Talk to your doctor about the risks of receiving omalizumab injection.
🔔 Why is this medication prescribed?
Omalizumab injection is used to decrease the number of asthma attacks (sudden episodes of wheezing, shortness of breath, and trouble breathing) in adults and children 6 years of age and older with allergic asthma (asthma caused by inhaling substances such as dander, pollen, and dust mites) whose symptoms are not controlled with inhaled steroids. It is also used to treat nasal polyps (swelling of the lining of the nose) in adults whose symptoms are not controlled with inhaled steroids. Omalizumab is also used to treat chronic hives without a known cause that cannot successfully be treated with antihistamine medications such as diphenhydramine (Benadryl), cetirizine (Zyrtec), hydroxyzine (Vistaril), and loratadine (Claritin) in adults and children 12 years of age and older. Omalizumab is not used to treat other forms of hives or allergic conditions. Omalizumab injection is in a class of medications called monoclonal antibodies. It works by blocking the action of a certain natural substance in the body that causes the symptoms of allergic asthma, nasal polyps, and hives.
🔔 How should this medicine be used?
Omalizumab injection comes as a prefilled syringe and as a powder to be mixed with water to be injected subcutaneously (under the skin). When omalizumab is used to treat allergic asthma or nasal polyps, it is usually injected once every 2 or 4 weeks. You may receive one or more injections, depending on your weight and medical condition. When omalizumab is used to treat chronic hives, it is usually given once every 4 weeks. Your doctor will determine the length of your treatment based on your condition and how well you respond to the medication.
The average length of the portion of a doctor appointment in which the patient actually sees the doctor is up from previous years, rising by about 12 seconds per year, according to Reuters. However, 60% of physicians report dissatisfaction with the amount of time they spend with their patients, athenaInsight Many doctors now spend more time on paperwork than seeing patients, and a primary care physician who spends 5 minutes of face-to-face time with a patient will spend another 19.3 minutes, on average, working on that patient’s electronic health records (EHRs).
If you will be injecting omalizumab injection by yourself at home or having a friend or relative inject the medication for you, your doctor will show you or the person who will be injecting the medication how to inject it. You and the person who will be injecting the medication should also read the written instructions for use that come with the medication.
Check the prefilled syringe to be sure that the expiration date printed on the package has not passed. Holding the syringe with the covered needle pointing down, look closely at the liquid in the syringe. The liquid should be clear and colorless to pale brownish yellow and should not be cloudy or discolored or contain lumps or particles. Call your pharmacist if there are any problems with the package or the syringe and do not inject the medication.
Allow the syringe to warm to room temperature for 15 to 30 minutes away from direct sunlight before you inject the medication. Do not try to warm the medication by heating it in a microwave, placing it in hot water, or through any other method. Inject omalizumab within 4 hours after taking it out of the refrigerator. Dispose of used syringe in a puncture-resistant container. Talk to your doctor or pharmacist about how to dispose of the puncture-resistant container.
Do not remove the cap from the prefilled syringe until you are ready to inject omalizumab. Do not replace the cap after you remove it. Do not use the syringe if you drop it on the floor.
You may inject omalizumab injection on the front of the thighs or anywhere on your stomach except your navel (belly button) and the area 2 inches around it. If another person is injecting your medication, the outer area of the upper arms also may be used. Do not inject the medication into skin that is tender, bruised, red, hard, or not intact, or that has scars, moles, or bruises. Choose a different spot each time you inject the medication, at least 1 inch away from a spot that you have used before. If the full dose is not injected, call your doctor or pharmacist.
It may take some time before you feel the full benefit of omalizumab injection. Do not decrease your dose of any other asthma, nasal polyps, or hives medication or stop taking any other medication that has been prescribed by your doctor unless your doctor tells you to do so. Your doctor may want to decrease the doses of your other medications gradually.
Omalizumab injection is not used to treat a sudden attack of asthma symptoms. Your doctor will prescribe a short-acting inhaler to use during attacks. Talk to your doctor about how to treat symptoms of a sudden asthma attack. If your asthma symptoms get worse or if you have asthma attacks more often, be sure to talk to your doctor.
