Posaconazole

Posaconazole is used to prevent serious fungal infections that can spread throughout the body in adults and children 2 years of age and older with a weakened ability to fight infection. Posaconazole delayed-release tablets are used to treat invasive aspergillosis (a serious fungal infection that begins in the lungs and spreads through the bloodstream to other organs) in adults and teenagers 13 years of age and older. Posaconazole oral suspension is also used to treat yeast infections of the mouth and throat including yeast infections in adults and teenagers 13 years of age and older that could not be treated successfully with other medications. Posaconazole is in a class of medications called azole antifungals. It works by slowing the growth of fungi that cause infection.

🔔 How should this medicine be used?

Posaconazole comes as an immediate-release oral suspension (liquid), as a delayed-release (releases the medication in the intestine to prevent break-down of the medication by stomach acids) tablet, and as a delayed-release oral suspension to take by mouth. The delayed-release tablets are usually taken with or without food twice daily on the first day and then once a day. The delayed-release oral suspension is usually taken with food twice daily on the first day and then once a day. The immediate-release oral suspension is usually taken one to three times a day with a full meal or within 20 minutes after a meal. If you cannot take the immediate-release oral suspension with a full meal, take it with a liquid nutritional supplement or an acidic carbonated drink such as ginger ale. Your doctor will determine how long you need to use this medication. Take posaconazole at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take posaconazole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the oral suspension well before each use to mix the medication evenly.

Always use the dosing spoon that comes with posaconazole immediate-release oral suspension to measure your dose. You may not receive the correct amount of medication if you use a household spoon to measure your dose. The spoon should be rinsed thoroughly with water after each use and before storing.

Swallow the posaconazole delayed-release tablets whole; do not split, chew, or crush them. If you cannot swallow the delayed-release tablets whole, tell your doctor.

If you or your child are using the delayed-release oral suspension, only use the mixing liquid that comes with the kit to prepare it. Add 9 mL of the mixing liquid to the delayed-release oral suspension powder. Shake the powder and liquid in the mixing cup vigorously for 45 seconds to mix. The mixture should look cloudy and not have any clumps. Once mixed, measure the dose with the syringe provided with the kit. Take the mixture with food within 1 hour of mixing. If you or your child are unable to take all of the dose or if some of the dose is spit out, call your doctor.

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Each posaconazole product releases the medication differently in your body and cannot be used interchangeably. Only take the posaconazole product prescribed by your doctor and do not switch to a different posaconazole product unless your doctor says that you should.

Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.