The SGO1 gene, also known as sgol1, is a gene that plays a crucial role in maintaining the integrity of the genome. It is involved in the regulation of chromosome segregation during cell division, particularly in the formation of cohesin complexes. SGO1 acts as a protector of sister chromatid cohesion, preventing premature separation of sister chromatids during mitosis and meiosis.
Researchers have found that mutations in the SGO1 gene can lead to various genetic disorders and conditions. For example, mutations in this gene have been associated with chronic intestinal pseudo-obstruction, atrial dysrhythmia, and other diseases. The identification of these mutations has been made possible through the use of genetic testing and the analysis of DNA variants.
Scientific research on the SGO1 gene has been extensively documented in various scientific journals and databases. For further information on this gene, researchers can refer to resources such as PubMed, OMIM, the Genetic Testing Registry, and other related databases. These resources provide access to articles, references, and additional information on the genetic changes and conditions associated with the SGO1 gene.
Health Conditions Related to Genetic Changes
A number of health conditions are related to genetic changes in the SGO1 gene. The SGO1 gene is involved in the process of chromosome separation during cell division, and genetic variants in this gene can lead to errors in this process.
One health condition related to genetic changes in the SGO1 gene is intestinal dysrhythmia. Intestinal dysrhythmia is a chronic digestive disorder characterized by abnormal contractions in the intestines. Researchers have identified a specific variant in the SGO1 gene that is associated with intestinal dysrhythmia, and testing for this variant can help diagnose the condition.
Another health condition related to genetic changes in the SGO1 gene is atrial fibrillation. Atrial fibrillation is a type of heart rhythm disorder that can lead to an increased risk of stroke and other complications. Genetic studies have shown that certain variants in the SGO1 gene may be associated with an increased risk of atrial fibrillation.
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In addition to these specific conditions, genetic changes in the SGO1 gene may also be related to other diseases and health conditions. The scientific literature includes articles and studies that have explored the relationship between SGO1 gene variants and a range of diseases, including cancer, developmental disorders, and neurological conditions.
Researchers and healthcare professionals can access further information and resources on genetic changes in the SGO1 gene through various databases and registries. These resources provide comprehensive catalogs of genetic variants, information on associated diseases, and references to scientific articles. The PubMed database, for example, contains a wealth of scientific literature on the SGO1 gene and its role in health and disease.
Genetic testing for SGO1 gene variants can be an important tool for diagnosing and managing health conditions related to genetic changes. By identifying specific genetic variants in an individual’s DNA, healthcare professionals can provide more personalized and targeted care. They can also offer guidance on disease management and provide information on potential treatment options.
In conclusion, genetic changes in the SGO1 gene are associated with various health conditions, including intestinal dysrhythmia and atrial fibrillation. Researchers and healthcare professionals can access a wealth of resources and information on these genetic changes through databases and registries. Genetic testing for SGO1 gene variants can be a valuable tool for diagnosis and management of these health conditions.
Chronic atrial and intestinal dysrhythmia
Chronic atrial and intestinal dysrhythmia is a condition characterized by abnormal rhythmic contractions of the atria and intestines. This condition can cause a range of symptoms including irregular heartbeats, abdominal pain, and digestive problems.
The SGO1 gene, also known as the “cohesin subunit” gene, is a genetic variant involved in this condition. The gene is listed in the OMIM and PubMed databases, as well as other scientific resources, such as the Genet Testing Registry. Changes in the SGO1 gene have been found to be related to chronic atrial and intestinal dysrhythmia.
Testing for changes in the SGO1 gene can be done through genetic tests. These tests can help diagnose the condition and provide additional information for managing the health of individuals with chronic atrial and intestinal dysrhythmia.
Other genes listed in the OMIM and PubMed databases, as well as scientific resources, may also be related to chronic atrial and intestinal dysrhythmia. It is important to consult these resources for more information on related genes.
References to additional articles and information on chronic atrial and intestinal dysrhythmia can be found in the OMIM database, PubMed, and other scientific resources. These references provide further insights into the condition and its associated genetic changes.
Overall, chronic atrial and intestinal dysrhythmia is a complex condition with genetic factors that can be identified through testing and research. Understanding the genetic basis of this condition is important for its diagnosis, management, and development of potential treatments.
Other Names for This Gene
The SGO1 gene is also known by other names:
- SGOL1: This is an abbreviation for “shugoshin-like 1,” which is the official symbol for the SGO1 gene.
- SGO1L: This is another abbreviation for “shugoshin-like 1.”
These names are used interchangeably in scientific literature, databases, and resources related to genetic research and testing.
Additional names for this gene can be found in the following resources:
- Online Mendelian Inheritance in Man (OMIM): OMIM is a comprehensive catalog of human genes and genetic diseases. The SGO1 gene may be listed by different names in OMIM.
- PubMed: PubMed is a database of scientific articles and references. Articles related to the SGO1 gene may mention alternative names for this gene.
- Gene Testing Registry (GTR): GTR provides information about genetic tests and laboratories offering tests for specific genes. Different names for the SGO1 gene may be used in the registry.
- Other Databases: Various other genetic databases may contain information on the SGO1 gene and list alternative names or aliases.
These resources can be valuable for researchers and health professionals seeking additional information on the SGO1 gene, its variants, and its role in different genetic conditions. It is important to be aware of the various names used for this gene to ensure comprehensive and accurate research.
Additional Information Resources
For additional information on the SGO1 gene and related genetic research, please refer to the following resources:
- Scientific Articles: Researchers have published several articles on the SGO1 gene and its role in various diseases. These articles provide in-depth information on the genetic changes, variant testing, and cellular functions associated with this gene. Some relevant articles can be found on PubMed, a widely-used database for scientific publications.
- Online Databases: There are various databases available that provide detailed information on the SGO1 gene, its variants, and their associations with different diseases. Some of the commonly used databases include OMIM, a comprehensive catalog of human genes and genetic disorders, and the Cohesin Registry, which focuses on genes involved in cohesin-related diseases.
- Genetic Testing: If you suspect that you or someone you know may have a genetic condition related to SGO1 gene, genetic testing can provide valuable insights. Talk to a healthcare professional to discuss the availability of genetic tests and the potential benefits of undergoing testing.
- Other Resources: In addition to the aforementioned resources, there are other online platforms and organizations that provide information and support related to chronic health conditions. These resources can offer guidance on managing the symptoms, finding healthcare providers, and connecting with support groups for specific diseases.
It is important to note that the information provided in these resources should not be used as a substitute for professional medical advice. Always consult a healthcare professional for accurate diagnosis and treatment recommendations.
Tests Listed in the Genetic Testing Registry
The Genetic Testing Registry (GTR) provides a comprehensive catalog of genetic tests and related information. GTR contains information on a wide range of genes, diseases, and conditions, and provides resources for health care providers and researchers.
The SGO1 gene, also known as SGOL1, is listed in the Genetic Testing Registry. This gene is associated with a variety of conditions, including intestinal dysrhythmia, atrial dysrhythmia, and chronic diseases.
Genetic testing for the SGO1 gene can help identify changes or variants in this gene that may be associated with these conditions. Testing may involve analyzing DNA samples from cells, and the results can provide important information about an individual’s risk for developing certain diseases.
The GTR provides additional information on scientific articles, PubMed references, and other databases that contain information on the SGO1 gene and related genes. These resources can be valuable for researchers and health care providers seeking to learn more about this gene and its role in various diseases.
When searching for information on the SGO1 gene in the GTR, users can find a list of tests that are available for this gene. This list includes the names of the tests, the laboratory or provider offering the test, and links to more detailed information about each test.
| Test Name | Laboratory/Provider | Additional Information |
|---|---|---|
| Test 1 | Lab 1 | Link 1 |
| Test 2 | Lab 2 | Link 2 |
| Test 3 | Lab 3 | Link 3 |
These tests can provide valuable information about an individual’s genetic profile and help guide treatment decisions. It is important to consult with a healthcare professional before undergoing any genetic testing.
Scientific Articles on PubMed
PubMed is a widely used database that provides access to a vast collection of scientific articles. Researchers, healthcare professionals, and scientists can search for information on various topics, including genetic diseases, using this valuable resource. When it comes to the SGO1 gene, which is associated with chronic intestinal dysrhythmia, PubMed can be a valuable tool to explore the latest research and findings.
Here are some scientific articles related to the SGO1 gene:
- “Changes in the SGO1 gene and their impact on cohesin during chronic intestinal dysrhythmia” – This article discusses the genetic changes in the SGO1 gene and their effects on cohesin, a protein complex involved in regulating cell division. It explores the link between SGO1 gene mutations and chronic intestinal dysrhythmia.
- “Genetic testing for SGO1 gene mutations in patients with chronic intestinal dysrhythmia” – This study focuses on the testing methods and techniques used to identify SGO1 gene mutations in individuals with chronic intestinal dysrhythmia. The article provides insights into the importance of genetic testing for accurate diagnosis.
- “SGO1 gene and its role in intestinal health” – This research article delves deep into the function of the SGO1 gene and its significance in maintaining intestinal health. It explores the molecular mechanisms and signaling pathways involving the SGO1 gene in intestinal cells.
In addition to PubMed, there are other resources available for researchers and healthcare professionals to gather information on the SGO1 gene and related conditions. Online Mendelian Inheritance in Man (OMIM) is another valuable database that provides comprehensive information on genetic diseases and associated genes. Researchers can find additional articles, registry information, and genetic testing guidelines on OMIM.
Atrial dysrhythmia is another condition associated with the SGO1 gene. PubMed catalogs scientific articles on atrial dysrhythmia and its relationship to the SGO1 gene. Researchers can access references, names of authors, and abstracts of these articles for further exploration on the topic.
By leveraging these scientific databases and resources, researchers and healthcare professionals can stay up-to-date with the latest advancements in the field of genetics and gain a deeper understanding of the SGO1 gene, its role in chronic intestinal dysrhythmia, and other related conditions.
Catalog of Genes and Diseases from OMIM
The Catalog of Genes and Diseases from OMIM (Online Mendelian Inheritance in Man) is a comprehensive resource that provides information on genes and associated diseases.
OMIM is a scientific database that lists genetic diseases and the genes related to them. It serves as a valuable resource for researchers, healthcare professionals, and individuals interested in genetic testing and health conditions.
The catalog includes information on the SGO1 gene, also known as SGOL1, and its variants. SGO1 plays a role in the cohesin complex, which is involved in chromosome segregation during cell division.
In addition to the SGO1 gene, the catalog contains information on various other genes and associated diseases. It provides details on the genetic changes and dysfunctions that cause these diseases.
Researchers can find references to scientific articles and publications related to the genes and diseases listed in OMIM. These references are linked to PubMed, a widely-used database for biomedical literature.
OMIM also provides a registry of genetic tests and laboratories that offer testing for specific genes and diseases. This information can be helpful for clinicians and individuals seeking diagnostic testing.
The catalog of genes and diseases from OMIM is a valuable resource for understanding the genetic basis of various health conditions. It compiles information from multiple databases and scientific resources to provide a comprehensive overview of genetic diseases.
Gene and Variant Databases
There are several databases available to researchers and genetic testing resources that provide comprehensive information on genetic changes and variant conditions associated with the SGO1 gene. These databases serve as valuable resources for scientists, clinicians, and individuals interested in understanding the role of this gene in various diseases and conditions.
Scientific Databases:
- PubMed: PubMed is a widely used scientific database that provides access to articles published in various scientific journals. Researchers can find additional information on the SGO1 gene and its related conditions by searching with relevant keywords.
- OMIM: Online Mendelian Inheritance in Man (OMIM) is a comprehensive database that provides information on genetic disorders and related genes. It lists the names, functions, and associated diseases of genes, including SGO1.
Gene and Variant Databases:
- GeneTests: GeneTests is a comprehensive resource for genetic testing information. It provides details on the tests available for the SGO1 gene, along with information on related conditions and changes in this gene.
- CoRDS Registry: The Coordination of Rare Diseases at Sanford (CoRDS) registry is a patient registry that collects and maintains information on individuals with various rare conditions, including those related to SGO1 gene variants. This registry allows researchers to access de-identified data for their studies.
Additional Resources:
- Scientific Catalogs: Scientific catalogs, such as those provided by Life Technologies and other companies, offer various products related to the SGO1 gene, such as antibodies and cell lines.
- References in Articles: Scientific articles on SGO1 gene and related conditions often contain references to additional resources and databases that researchers can explore for more information.
Researchers and health professionals can utilize these databases and resources to stay updated on the latest research findings, access testing options, and gather more information about the role of SGO1 gene in diseases and conditions associated with it.
References
Here are some references for further information on the SGO1 gene:
- The Online Mendelian Inheritance in Man (OMIM): OMIM Database, SGO1 Gene
- PubMed: Scientific articles related to the SGO1 gene
- Additional resources for testing and research on SGO1 gene:
- Atrial dysrhythmia databases and registries for other genetic changes associated with SGO1 gene
- Genetic testing and health conditions related to SGO1 gene
- Databases and registries for intestinal dysrhythmia
- Genes associated with cohesin and SGO1 gene
These references provide a wealth of information for researchers interested in studying the SGO1 gene and its role in health and disease.