Teprotumumab-trbw Injection

Teprotumumab-trbw injection is used to treat thyroid eye disease (TED; Graves’ eye disease; a disorder in which the immune system causes inflammation and swelling behind the eye). Teprotumumab-trbw is in a class of medications called monoclonal antibodies. It works by blocking the action of a certain protein in the body that causes inflammation in the eye.

🔔 How should this medicine be used?

Teprotumumab-trbw injection comes as a powder to be mixed with liquid and injected intravenously (into a vein) by a doctor or nurse in a medical office or hospital. It is usually injected slowly over a period of 60 to 90 minutes on day 1 of a 21 day cycle. The cycle may be repeated 7 times.

You may experience a reaction during or shortly after you receive a dose of teprotumumab-trbw injection. You may receive certain medications before your infusion to prevent a reaction if you had a reaction with previous treatment. Tell your doctor immediately if you experience any of these symptoms during or within 90 minutes after you receive treatment: feeling hot, rapid heartbeat, shortness of breath, headache, and muscular pain.

Your doctor may slow down your infusion, stop your treatment with teprotumumab-trbw injection, or treat you with additional medications depending on your response to the medication and any side effects that you experience. Talk to your doctor about how you are feeling during and after your treatment.

Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.

🔔 Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Part of the reason for these long wait times and short appointments is due to a nationwide shortage of physicians that is only getting worse. A report by the Association of American Medical Colleges predicts that, due to population growth and specifically growth of the elderly population, the physician shortfall in the U.S. could reach 121,300 by the year 2030.

🔔 What special precautions should I follow?

Before receiving teprotumumab-trbw,

• tell your doctor and pharmacist if you are allergic to teprotumumab-trbw, any other medications, or any of the ingredients in teprotumumab-trbw injection. Ask your pharmacist for a list of the ingredients.
• tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
• tell your doctor if you have or have ever had inflammatory bowel disease, impaired fasting glucose (pre-diabetes), or diabetes.
• tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while you are receiving teprotumumab-trbw injection and for at least 6 months after your final dose. Talk to your doctor about birth control methods that will work for you. If you become pregnant while receiving teprotumumab-trbw injection, call your doctor immediately. Teprotumumab-trbw injection may harm the fetus.
• tell your doctor if you are breastfeeding or plan to breastfeed.

🔔 What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.