Understanding How Hyperthyroidism and Hypercalcemia Are Connected

Hyperthyroidism can cause many symptoms, and hypercalcemia is among them. However, both are treatable with medications and lifestyle changes.

Hyperthyroidism is a condition that causes your thyroid to produce too much thyroid hormone. This speeds up your metabolism and results in symptoms like heart palpations, fatigue, unintentional weight loss, and insomnia.

Sometimes hyperthyroidism can also cause blood calcium levels to rise. This is a condition called hypercalcemia.

In severe cases, hypercalcemia can be a medical emergency, but hyperthyroidism very rarely causes this type of hypercalcemia. Typically, hyperthyroidism leads to mild or moderate hypercalcemia that causes minimal symptoms, this type can easily be treated with medication.

There’s a link between hyperthyroidism and hypercalcemia. Around 20% of people with hyperthyroidism also develop hypercalcemia.

In most cases, hyperthyroidism leads to mild or moderate hypercalcemia. It’s rare for hyperthyroidism to cause severe hypercalcemia.

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Research has shown that thyroid hormones influence serum calcium levels in the body. When your body produces an excessive amount of thyroid hormone, as it does in hyperthyroidism, it can lead to excess production of serum calcium. This can cause hypercalcemia.

The symptoms of hyperthyroidism and hypercalcemia can sometimes mask each other.

Sometimes people with mild hypercalcemia do not have any symptoms. People with hyperthyroidism and mild hypercalcemia might not notice they have hypercalcemia. They might not be aware of the condition unless it shows up in routine blood tests.

Hyperthyroidism and hypercalcemia share these symptoms:

Additional symptoms of hypercalcemia can include :

Additional symptoms of hyperthyroidism include:

  • unintentional weight loss
  • Increased hunger
  • heart palpations
  • An irregular or fast heartbeat
  • Frequent bowel movements
  • Irritation
  • anxiety
  • Sweating
  • heat intolerance
  • insomnia
  • changes to your menstrual cycle
  • thinning skin
  • hair becoming brittle and fine
  • Enlargement of the thyroid gland that appears as a visible swelling or lump at the base of the neck

Hyperthyroidism treatment typically involves medication therapy. In severe cases, surgery might be an option. There are also medications that can help treat hypercalcemia. Since hyperthyroidism-induced hypercalcemia is typically mild, a medication that lowers calcium blood levels is often a good choice.

Calcitonin is commonly used to treat hypercalcemia that hyperthyroidism causes. This medication can lower calcium levels and treat symptoms of hypercalcemia.

Treatment for hyperthyroidism will also continue. Treatment options for hyperthyroidism include:

  • Antithyroid medications: Antithyroid medications cause the thyroid to make less thyroid hormone.
  • Beta-blockers:Beta-blockers are prescribed to reduce the symptoms of hyperthyroidism.
  • Radioiodine therapy: Taking radioactive iodine capsules or liquid can destroy thyroid hormone-producing cells.
  • Surgery: When medications are not enough, surgery to remove part or all of the thyroid is an option.
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Your doctor might also recommend that you follow some dietary guidelines until your calcium levels are at a recommended level. This often includes:

  • drinking more water
  • avoiding or limiting dairy
  • avoiding foods with added calcium
  • avoiding over-the-counter antacids

You can also help manage your hyperthyroidism symptoms with a nutritious diet. Some of the best foods for people with hyperthyroidism include:

Living with hyperthyroidism

Hyperthyroidism can be a challenging condition to manage, but there are places you can turn to for support. If you’ve been diagnosed with hyperthyroidism, these organizations are a great place to start:

  • ThyroidChange: If you’re looking for personalized care, ThyroidChange can help you find it and will advocate to help ensure you receive it.
  • The Grave’s Disease and Thyroid Foundation: The Grave’s Disease and Thyroid Foundation offers support groups, educational materials, connections to local resources, and more.
  • The American Thyroid Association (ATA): You can find patient resources, local endocrine specialists, and information about clinical trials when you visit the ATA website.

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