Tepotinib

Tepotinib is used to treat a certain type of non-small cell lung cancer (NSCLC) that has spread to other parts of the body in adults. Tepotinib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps slow or stop the spread of cancer cells.

🔔 How should this medicine be used?

Tepotinib comes as a tablet to take by mouth. It is usually taken once daily with food. Take tepotinib at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take tepotinib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the tablets whole; do not split, chew, or crush them.

If you cannot swallow the tablets whole, place the tablets in a glass of 1 ounce (30 mL) of non-carbonated water. Do not use any other liquids other than water. Stir until the tablets are in small pieces. Do not crush the tablets; they will not completely dissolve. Drink the mixture right away or within 1 hour of preparing. Do not chew pieces of the tablet. Rinse the glass with an additional 1 ounce (30 mL) of water and drink to make sure that you have taken the full dose.

If you have a nasogastric (NG) tube, your doctor or pharmacist will explain how to give tepotinib through a NG tube.

If you vomit after taking tepotinib, do not take another dose. Continue your regular dosing schedule.

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Your doctor may decrease your dose or temporarily or permanently stop your treatment depending on if you experience any side effects. Be sure to tell your doctor how you are feeling during your treatment with tepotinib.

🔔 Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

🔔 What special precautions should I follow?

Before taking tepotinib,

• tell your doctor and pharmacist if you are allergic to tepotinib, any other medications, or any of the ingredients in tepotinib tablets. Ask your pharmacist for a list of the ingredients.
• tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
• tell your doctor if you have or have ever had lung or breathing problems other than lung cancer or liver disease.
• tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while you are taking tepotinib. You will need to have a pregnancy test before you start treatment, and you should use birth control to prevent pregnancy during your treatment and for at least 1 week after your final dose. If you are a male with a female partner who may become pregnant, you should use birth control to prevent pregnancy during you treatment and for at least 1 week after your final dose. Talk to your doctor about birth control methods that will work for you. Tepotinib may harm your unborn baby. If you or your partner become pregnant during your treatment with tepotinib, call your doctor immediately.
• tell your doctor if you are breast-feeding. You should not breast-feed while you are taking tepotinib and for at least 1 week after your final dose.

🔔 What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.